Palmitoleoyl 3-carbacyclic phosphatidic acid
Palmitoleoyl 3-carbacyclic phosphatidic acid (3ccPA 16:1) is an intermediately potent inhibitor of autotaxin (ATX) with an IC50 of 620 nM. Palmitoleoyl 3-carbacyclic phosphatidic acid can be used for melanoma research[1].
Product Specifications
CAS Number
910228-13-6
UNSPSC
12352005
Hazard Statement
H225-H302-H310-H315-H319-H331-H351-H361-H372
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/palmitoleoyl-3-carbacyclic-phosphatidic-acid.html
Solubility
10 mM in DMSO
Smiles
CCCCCC/C=C\CCCCCCCC(OCC1OP(O)(CC1)=O)=O
Molecular Formula
C20H37O5P
Molecular Weight
388.48
Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P262-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Baker DL, et al. Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. J Biol Chem. 2006 Aug 11;281 (32) :22786-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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