Palmitoleoyl 3-carbacyclic phosphatidic acid

Palmitoleoyl 3-carbacyclic phosphatidic acid (3ccPA 16:1) is an intermediately potent inhibitor of autotaxin (ATX) with an IC50 of 620 nM. Palmitoleoyl 3-carbacyclic phosphatidic acid can be used for melanoma research[1].

Product Specifications

CAS Number

[910228-13-6]

UNSPSC

12352005

Hazard Statement

H225-H302-H310-H315-H319-H331-H351-H361-H372

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/palmitoleoyl-3-carbacyclic-phosphatidic-acid.html

Solubility

10 mM in DMSO

Smiles

CCCCCC/C=C\CCCCCCCC(OCC1OP(O)(CC1)=O)=O

Molecular Formula

C20H37O5P

Molecular Weight

388.48

Precautions

P210-P233-P240-P241-P242-P243-P260-P261-P262-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Baker DL, et al. Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis. J Biol Chem. 2006 Aug 11;281 (32) :22786-93.