N-Nitrosodicyclohexylamine

N-Nitrosodicyclohexylamine (NDCHA) is a N-nitrosocompound with anti-androgenic activities. N-Nitrosodicyclohexylamine shows the competitive binding to androgen receptor (AR) against 5α-dihydrotestosterone and decreased the level of AR protein[1].

Product Specifications

CAS Number

[947-92-2]

Product Name Alternative

NDCHA

UNSPSC

12352211

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/n-nitrosodicyclohexylamine.html

Concentration

10mM

Purity

99.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=NN(C1CCCCC1)C2CCCCC2

Molecular Formula

C12H22N2O

Molecular Weight

210.32

References & Citations

[1]Hari, Sayaka, et al. (2006) . Anti-Androgenic Activity of N-Nitrosodibenzylamine, N-Nitrosodiphenylamine and N-Nitrosodicyclohexylamine. JOURNAL OF HEALTH SCIENCE, 52 (5), 522-531.