5'-TMPS
5'-TMPS (Thymidine-5'-O-monophosphorothioate) is a selective partial agonist of P2Y6R and an antagonist of P2Y14R. Additionally, 5'-TMPS acts as a positive regulator of angiogenesis, exhibiting pro-angiogenic effects[1][2]
Product Specifications
CAS Number
[15548-51-3]
Product Name Alternative
Thymidine-5'-O-monophosphorothioate
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-tmps.html
Smiles
O=C(C(C)=CN1[C@H]2C[C@H](O)[C@@H](COP(O)(S)=O)O2)NC1=O
Molecular Formula
C10H15N2O7PS
Molecular Weight
338.27
References & Citations
[1]Rafehi M, et al. Tools and drugs for uracil nucleotide-activated P2Y receptors[J]. Pharmacology & Therapeutics, 2018, 190: 24-80.|[2]Węgłowska E, et al. Extracellular nucleotides affect the proangiogenic behavior of fibroblasts, keratinocytes, and endothelial cells[J]. International Journal of Molecular Sciences, 2021, 23 (1) : 238.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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