Chlorin e6

Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer[1][2][3].

Product Specifications

CAS Number

[19660-77-6]

Product Name Alternative

Ce6

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bcl-2 Family; Caspase; Fluorescent Dye; PARP

Type

Dye Reagents

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/chlorin-e6.html

Purity

99.51

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

OC(C/C1=C2[C@H]([C@@H](C(/C=C3N/C(C(C=C)=C\3C)=C\C4=N/C(C(CC)=C4C)=C\C5=C(C)C(C(O)=O)=C1N5)=N\2)C)CCC(O)=O)=O

Molecular Formula

C34H36N4O6

Molecular Weight

596.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Nie M, et al. Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm [J]. Photodiagnosis and photodynamic therapy, 2020, 31: 101817.|[2]Karuppusamy S, et al. Nanoengineered chlorin e6 conjugated with hydrogel for photodynamic therapy on cancer [J]. Colloids and Surfaces B: Biointerfaces, 2019, 181: 778-788.|[3]Shrestha R, et al. Effect of Photodynamic Therapy with Chlorin e6 on Canine Tumors [J]. Life, 2022, 12 (12) : 2102.