Valecobulin
Valecobulin (CKD516) is a valine proagent of (S516) and a vascular disrupting agent (VDA) . Valecobulin is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors[1][2].
Product Specifications
CAS Number
1188371-47-2
Product Name Alternative
CKD-516
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Valecobulin.html
Purity
98.47
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C)[C@H](N)C(NC1=NC(C2=CC=C(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C(N4N=CN=C4)=C2)=CS1)=O
Molecular Formula
C26H28N6O5S
Molecular Weight
536.60
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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