Autophagy-IN-6
Autophagy-IN-6 (compound 1u) is a lysosomotropic autophagy inhibitor and can induces LC3-II protein accumulation. Autophagy-IN-6 shows anti-proliferative activity[1].
Product Specifications
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-in-6.html
Smiles
O=C(NCCCCCC)C[C@@H](C1)[C@H]([C@@H](OC(C(C)C)=O)C2)[C@H](C3)[N@@]1[C@@H]2CN3CC4=CC=CC=C4
Molecular Formula
C28H43N3O3
Molecular Weight
469.66
References & Citations
[1]Miura K, et al. Discovery of sp3-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors. Eur J Med Chem. 2024 Oct 5;280:116923.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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