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Autophagy-IN-6

Product Specifications

UNSPSC Description

Autophagy-IN-6 (compound 1u) is a lysosomotropic autophagy inhibitor and can induces LC3-II protein accumulation. Autophagy-IN-6 shows anti-proliferative activity[1].

Target Antigen

Autophagy

Type

Reference compound

Related Pathways

Autophagy

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/autophagy-in-6.html

Smiles

O=C(NCCCCCC)C[C@@H](C1)[C@H]([C@@H](OC(C(C)C)=O)C2)[C@H](C3)[N@@]1[C@@H]2CN3CC4=CC=CC=C4

Molecular Weight

469.66

References & Citations

[1]Miura K, et al. Discovery of sp3-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors. Eur J Med Chem. 2024 Oct 5;280:116923.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-168206/Autophagy-IN-6-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-168206/

Clinical Information

No Development Reported

Curated Selection

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