Ketone monoester

Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes[1][2][3].

Product Specifications

CAS Number

[1208313-97-6]

UNSPSC

12352211

Hazard Statement

H318

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ketone-monoester.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

C[C@@H](O)CC(OCC[C@H](O)C)=O

Molecular Formula

C8H16O4

Molecular Weight

176.21

Precautions

H318

References & Citations

[1]Weckx R, et al. Efficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness. Sci Rep. 2022 Jun 22;12 (1) :10591.|[2]Williams MS, et al. The Chemistry of the Ketogenic Diet: Updates and Opportunities in Organic Synthesis. Int J Mol Sci. 2021 May 15;22 (10) :5230.|[3]Clarke K, et al. Oral 28-day and developmental toxicity studies of (R) -3-hydroxybutyl (R) -3-hydroxybutyrate. Regul Toxicol Pharmacol. 2012 Jul;63 (2) :196-208.