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Anti-TNBC agent-1

Anti-TNBC agent-1 is a potent anti-triple-negative breast cancer (TNBC) agent. anti-TNBC agent-1 exhibits potent activity against different breast cancer cells with IC50 values ranging from 0.20 μM to 0.27 μM. anti-TNBC agent-1 induces apoptosis of SUM-159 cells through mitochondria pathway and causes G1 phase arrest of SUM-159 cells[1].

Product Specifications

CAS Number

2289585-58-4

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anti-tnbc-agent-1.html

Purity

98.02

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@]1(CC/C=C2COC(/C=C/C(C(OC)=CC=C3)=C3OC)=O)[C@@](O1)([H])[C@](OC4=O)([H])[C@](CC/2)([H])C4=C

Molecular Formula

C26H30O7

Molecular Weight

454.51

References & Citations

[1]Ge W, et al. Synthesis and structure-activity relationship studies of parthenolide derivatives as potential anti-triple negative breast cancer agents. Eur J Med Chem. 2019;166:445-469.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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