SCR-1481B1
SCR-1481B1 (Metatinib anhydrous) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.
Product Specifications
CAS Number
[1174161-86-4]
Product Name Alternative
Metatinib (anhydrous) ; c-Met inhibitor 2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-Met-inhibitor-2.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CN(COP(O)(O)=O)C=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(C(F)=C3)OC4=C(Cl)C(N)=NC=C4.OCC(CO)(CO)N.OCC(CO)(CO)N
Molecular Formula
C32H40ClF2N6O13P
Molecular Weight
821.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Robert M. Borzilleri, et al. 4-pyridinone compounds and their use for cancer. WO/2009094417/A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR1/Flt-1
Available Sizes
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