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(R) -PF-04991532

(R) -PF-04991532 is the R-enantiomer of PF-04991532. PF-04991532 is a potent, hepatoselective glucokinase activator[1].

Product Specifications

UNSPSC

12352005

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/r-pf-04991532.html

Purity

98.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(NC([C@H](N2C=C(C(F)(F)F)N=C2)CC3CCCC3)=O)N=C1)O

Molecular Formula

C18H19F3N4O3

Molecular Weight

396.36

References & Citations

[1]Erion DM, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. PLoS One. 2014 May 23;9 (5) :e97139.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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