(R) -PF-04991532
(R) -PF-04991532 is the R-enantiomer of PF-04991532. PF-04991532 is a potent, hepatoselective glucokinase activator[1].
Product Specifications
UNSPSC
12352005
Target
Drug Isomer
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/r-pf-04991532.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(NC([C@H](N2C=C(C(F)(F)F)N=C2)CC3CCCC3)=O)N=C1)O
Molecular Formula
C18H19F3N4O3
Molecular Weight
396.36
References & Citations
[1]Erion DM, et al. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats. PLoS One. 2014 May 23;9 (5) :e97139.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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