DNA Ligase I Antibody Clone 4

<strong>DNA Ligase I Antibody Clone 4</strong>_x000D_ <strong>Catalog number:</strong> B2015110_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 133 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> DNA Ligase I Antibody Clone 4_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Teraoka H, Tsukada K. Eukaryotic DNA ligase. Purification and properties of the enzyme from bovine thymus, and immunochemical studies of the enzyme from animal tissues J Biol Chem. 1982 May 10;257(9):4758-63._x000D_ 2: Söderhäll S, Lindahl T. Mammalian DNA ligases. Serological evidence for two separate enzymes J Biol Chem. 1975 Nov 10;250(21):8438-44._x000D_ 3: Elder RH, Rossignol JM. DNA ligases from rat liver. Purification and partial characterization of two molecular forms Biochemistry. 1990 Jun 26;29(25):6009-17._x000D_ 4: Hammel M, Tainer JA. X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology Protein Sci. 2021 Sep;30(9):1735-1756._x000D_ 5: Loor G, Zhang SJ, Zhang P, Toomey NL, Lee MY. Identification of DNA replication and cell cycle proteins that interact with PCNA Nucleic Acids Res. 1997 Dec 15;25(24):5041-6._x000D_ 6: Huang M, Dong G, Lu X, Xiao F, Zhou Q, Zhang S. DNA ligase IV dificiency with elevated serum IgG levels suspected to have myelodysplastic syndrome: a case report BMC Pediatr. 2022 Oct 11;22(1):588._x000D_ 7: Tobin LA, Robert C, Rapoport AP, Gojo I, Baer MR, Tomkinson AE, Rassool FV. Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias Oncogene. 2013 Apr 4;32(14):1784-93._x000D_ 8: Pan-Hammarström Q, Jones AM, Lähdesmäki A, Zhou W, Gatti RA, Hammarström L, Gennery AR, Ehrenstein MR. Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells J Exp Med. 2005 Jan 17;201(2):189-94._x000D_ 9: Arrand JE, Willis AE, Goldsmith I, Lindahl T. Different substrate specificities of the two DNA ligases of mammalian cells J Biol Chem. 1986 Jul 15;261(20):9079-82._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10696234">10: Thyagarajan B, Lundberg R, Rafferty M, Campbell C. Nucleolin promotes homologous DNA pairing in vitro Somat Cell Mol Genet. 1998 Sep;24(5):263-72. </a>_x000D_ _x000D_ <strong>Products Related to DNA Ligase I Antibody Clone 4 can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>