Garcinone E

Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas[1].

Product Specifications

CAS Number

[112649-21-5]

UNSPSC

12352005

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/garcinone-e.html

Purity

98.19

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(OC3=C1C(O)=C(C/C=C(C)\C)C(O)=C3)C(C/C=C(C)\C)=C(O)C(O)=C2C/C=C(C)\C

Molecular Formula

C28H32O6

Molecular Weight

464.55

References & Citations

[1]Linli Yang, et al. Garcinone-E exhibits anticancer effects in HeLa human cervical carcinoma cells mediated via programmed cell death, cell cycle arrest and suppression of cell migration and invasion. AMB Express. 2020 Jul 16;10 (1) :126.