CellTracker Blue CMAC

CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm) . CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels[1][2][3].

Product Specifications

CAS Number

[147963-22-2]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/celltracker-blue-cmac.html

Purity

98.84

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1OC2=C(C(CCl)=C1)C=CC(N)=C2

Molecular Formula

C10H8ClNO2

Molecular Weight

209.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Horobin R W, et al. Reactive dyes for living cells: Applications, artefacts, and some comparisons with textile dyeing. Coloration technology, 2022,138 (1) :3-15.|[2]King N, et al. A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes. J Pharmacol Toxicol Methods. 2004 Nov-Dec;50 (3) :215-22. |[3]Dludla PV, et al. A dose-dependent effect of dimethyl sulfoxide on lipid content, cell viability and oxidative stress in 3T3-L1 adipocytes. Toxicol Rep. 2018 Oct 4;5:1014-1020.