Gliadin p31-43

Gliadin p31-43 is an undigested gliadin peptide. Gliadin p31-43 induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 can be used for celiac disease research[1][2].

Product Specifications

CAS Number

[176326-01-5]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/gliadin-p31-43.html

Purity

98.18

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N2[C@@H](CCC2)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)[C@H]4N(CCC4)C([C@H](CC5=CC=CC=C5)NC([C@H]6N(CCC6)C([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC(CNC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C71H102N18O20

Molecular Weight

1527.68

References & Citations

[1]Merlin Nanayakkara, et al. P31-43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease. Sci Rep. 2018 Jul 17;8 (1) :10821.|[2]María Florencia Gómez Castro, et al. p31-43 Gliadin Peptide Forms Oligomers and Induces NLRP3 Inflammasome/Caspase 1- Dependent Mucosal Damage in Small Intestine. Front Immunol. 2019 Jan 30;10:31.