N-Arachidonylglycine-d8
N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine[1]. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM) . Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM) . N-Arachidonylglycine also is an effective activator of endometrial cell migration[2][3].
Product Specifications
CAS Number
1159908-44-7
Product Name Alternative
NA-Gly-d8
UNSPSC
12352211
Target
Endogenous Metabolite; GlyT; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Concentration
2.71 mM * 1 mL in Ethanol
Purity
98.1
Smiles
OC(CNC(CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)=O)=O
Molecular Formula
C22H27D8NO3
Molecular Weight
369.57
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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