Bempedoic acid
Product Specifications
Product Name Alternative
ETC-1002; ESP-55016
UNSPSC Description
Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2].
Target Antigen
AMPK; ATP Citrate Lyase
Type
Reference compound
Related Pathways
Epigenetics;Metabolic Enzyme/Protease;PI3K/Akt/mTOR
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ETC-1002.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C(C)(C)CCCCCC(O)CCCCCC(C)(C)C(O)=O
Molecular Weight
344.49
References & Citations
[1]Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54(1):134-51.|[2]Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54(8):2095-108.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12357/Bempedoic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12357/Bempedoic-acid-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
738606-46-7
Available Sizes
Curated Selection
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