Amenamevir
Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
Product Specifications
CAS Number
[841301-32-4]
Product Name Alternative
ASP2151
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Amenamevir.html
Purity
99.92
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(C(CC1)CCS1(=O)=O)N(C2=C(C)C=CC=C2C)CC(NC3=CC=C(C4=NOC=N4)C=C3)=O
Molecular Formula
C24H26N4O5S
Molecular Weight
482.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57 (3) :1339-46.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HSV-1; HSV-2
Available Sizes
Curated Selection
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