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Amenamevir

Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.

Product Specifications

CAS Number

841301-32-4

Product Name Alternative

ASP2151

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Amenamevir.html

Purity

99.92

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O=C(C(CC1)CCS1(=O)=O)N(C2=C(C)C=CC=C2C)CC(NC3=CC=C(C4=NOC=N4)C=C3)=O

Molecular Formula

C24H26N4O5S

Molecular Weight

482.55

Precautions

H302, H315, H319, H335

References & Citations

[1]Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57 (3) :1339-46.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

HSV-1; HSV-2

Available Sizes

Frequently Asked Questions

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