CM-675
CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer’s disease[1].
Product Specifications
CAS Number
1872466-47-1
Product Name Alternative
ONO1101 (hydrochloride),BMS-189453
UNSPSC
12352005
Target
HDAC; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cm-675.html
Concentration
10mM
Purity
99.53
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=CC=C1N)C2=CC=C(CC3=CC=C(OCC)C(C4=NC5=C(N(C)N=C5CCC)C(N4)=O)=C3)C=C2
Molecular Formula
C31H32N6O3
Molecular Weight
536.62
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; PDE5
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human Thioredoxin-2/TXN2 Protein (His Tag)
