CM-675
CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer’s disease[1].
Product Specifications
CAS Number
1872466-47-1
Product Name Alternative
ONO1101 (hydrochloride),BMS-189453
UNSPSC
12352005
Target
HDAC; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cm-675.html
Concentration
10mM
Purity
99.53
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=CC=C1N)C2=CC=C(CC3=CC=C(OCC)C(C4=NC5=C(N(C)N=C5CCC)C(N4)=O)=C3)C=C2
Molecular Formula
C31H32N6O3
Molecular Weight
536.62
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; PDE5
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human Creatine Kinase, Muscle (CKM) ELISA Kit
Human Creatine Kinase, Muscle (CKM) ELISA Kit
CD163 (Monocyte & Macrophage Marker) (M130/1210), CF488A conjugate, 0.1mg/mL
![(S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid](https://cdn.genprice.uk/products/572/1037745020493/imageurl/trc-a609335-50mg.webp)