ZD7288
ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker[1].
Product Specifications
CAS Number
[133059-99-1]
Product Name Alternative
ICI D7288
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HCN Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ZD7288.html
Purity
99.77
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
[H]Cl.C/N=C1C=C(N(CC)C2=CC=CC=C2)N=C(C)N/1C
Molecular Formula
C15H21ClN4
Molecular Weight
292.81
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang XX, et al. ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity. Neural Regen Res. 2016 May;11 (5) :779-86.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6187219-01 0.1 mL
SLC44A2 (Solute Carrier Family 44, Member 2, CTL2, DKFZp666A071, FLJ44586, PP1292) (PE)
Ask
View Details 
MBS6187219-02 5x 0.1 mL
SLC44A2 (Solute Carrier Family 44, Member 2, CTL2, DKFZp666A071, FLJ44586, PP1292) (PE)
Ask
View Details 
MBS1443077-01 0.02 mg (E-Coli)
Recombinant Helicobacter hepaticus UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG)
Ask
View Details MBS1443077-02 0.02 mg (Yeast)
Recombinant Helicobacter hepaticus UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG)
Ask
View Details MBS1443077-03 0.1 mg (E-Coli)
Recombinant Helicobacter hepaticus UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG)
Ask
View Details