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Baminercept

Product Specifications

UNSPSC Description

Baminercept (BG 9924) is a lymphotoxin β receptor IgG fusion protein (LTβR-Ig). Baminercept can be used for the research of many autoimmune diseases including primary Sjögren's syndrome (SS) and rheumatoid arthritis (RA) [1][2].

Target Antigen

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/baminercept.html

Purity

99.9

Solubility

10 mM in DMSO

Smiles

[Baminercept]

References & Citations

[1]E William St Clair, et al. Clinical Efficacy and Safety of Baminercept, a Lymphotoxin β Receptor Fusion Protein, in Primary Sjögren's Syndrome: Results From a Phase II Randomized, Double-Blind, Placebo-Controlled Trial. Arthritis Rheumatol. 2018 Sep;70(9):1470-1480.|[2]Jadwiga Bienkowska, et al. Lymphotoxin-LIGHT pathway regulates the interferon signature in rheumatoid arthritis. PLoS One. 2014 Nov 18;9(11):e112545.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99459/Baminercept-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99459/Baminercept-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

CAS Number

909110-25-4

Available Sizes

Curated Selection

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