HIV Protease FRET Substrate I

<strong>HIV Protease FRET Substrate I</strong>_x000D_ <strong>Catalog number:</strong> B2011376_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1532.8 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> HIV Protease Substrate I_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Beck ZQ, Morris GM, Elder JH. Defining HIV-1 protease substrate selectivity Curr Drug Targets Infect Disord. 2002 Mar;2(1):37-50._x000D_ 2: Kolli M, Ozen A, Kurt-Yilmaz N, Schiffer CA. HIV-1 protease-substrate coevolution in nelfinavir resistance J Virol. 2014 Jul;88(13):7145-54._x000D_ 3: Laco GS. HIV-1 protease substrate-groove: Role in substrate recognition and inhibitor resistance Biochimie. 2015 Nov;118:90-103._x000D_ 4: Rusere LN, Lockbaum GJ, Lee SK, Henes M, Kosovrasti K, Spielvogel E, Nalivaika EA, Swanstrom R, Yilmaz NK, Schiffer CA, Ali A. HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope J Med Chem. 2019 Sep 12;62(17):8062-8079._x000D_ 5: Ahsan M, Pindi C, Senapati S. Electrostatics Plays a Crucial Role in HIV-1 Protease Substrate Binding, Drugs Fail to Take Advantage Biochemistry. 2020 Sep 15;59(36):3316-3331._x000D_ 6: Deshmukh L, Tugarinov V, Louis JM, Clore GM. Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9855-E9862._x000D_ 7: Ozen A, Haliloğlu T, Schiffer CA. Dynamics of preferential substrate recognition in HIV-1 protease: redefining the substrate envelope J Mol Biol. 2011 Jul 22;410(4):726-44._x000D_ 8: Trylska J, Tozzini V, Chang CE, McCammon JA. HIV-1 protease substrate binding and product release pathways explored with coarse-grained molecular dynamics Biophys J. 2007 Jun 15;92(12):4179-87._x000D_ 9: Potempa M, Lee SK, Wolfenden R, Swanstrom R. The triple threat of HIV-1 protease inhibitors Curr Top Microbiol Immunol. 2015;389:203-41._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26982200">10: Benko Z, Elder RT, Li G, Liang D, Zhao RY. HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe PLoS One. 2016 Mar 16;11(3):e0151286. </a>_x000D_ _x000D_ <strong>Products Related to HIV Protease FRET Substrate I can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>