AA863

AA863 is a 5-lipoxygenase inhibitor with activity in inhibiting the proliferation of human glioma cells. AA863 exhibits significant and dose-dependent inhibitory effects in monolayer cultured glioma cells with an IC50 of 9.0 micromolar[1].

Product Specifications

CAS Number

80809-95-6

UNSPSC

12352211

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aa863.html

Smiles

O=C1C(CCCCC#CCCCC#CCO)=C(C(C(OC)=C1OC)=O)C

Molecular Formula

C21H26O5

Molecular Weight

358.43

References & Citations

[1]Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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