RAD16-I (hydrochloride)

RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes[1]. RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs[2].

Product Specifications

CAS Number

[2100275-49-6]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rad16-i-hydrochloride.html

Purity

98.88

Solubility

H2O : 7.7 mg/mL (ultrasonic; warming)

Smiles

NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.Cl

Molecular Formula

C66H113N29O25.xHCl

References & Citations

[1]Gerard Rubí-Sans, et al. Development of a Three-Dimensional Bioengineered Platform for Articular Cartilage Regeneration. Biomolecules. 2019 Dec 28;10 (1) :52.|[2]Yongzhu Chen, et al. Amyloid-like staining property of RADA16-I nanofibers and its potential application in detecting and imaging the nanomaterial. Int J Nanomedicine. 2018 Apr 23;13:2477-2489.