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5′-Guanylyl methylenediphosphonate (sodium)

5′-Guanylyl methylenediphosphonate (sodium) is a GTP analogue and a specific, competitive inhibitor of the GTP reaction in protein synthesis[1].

Product Specifications

CAS Number

[10470-57-2]

Product Name Alternative

β, γ-Methylene-GTP (sodium)

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-guanylyl-methylenediphosphonate-sodium.html

Purity

99.00

Solubility

H2O : ≥ 100 mg/mL

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=C(C(N=C(N3)N)=O)N=C2)O[C@@H]1COP(OP(CP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Molecular Formula

C11H15N5Na3O13P3

Molecular Weight

587.15

References & Citations

[1]Hershey JW, et.al. A competitive inhibitor of the GTP reaction in protein synthesis. J Mol Biol. 1966 Jun;18 (1) :68-76.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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