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Bazedoxifene (acetate) (Standard)

Bazedoxifene (acetate) (Standard) is the analytical standard of Bazedoxifene (acetate) . This product is intended for research and analytical applications. Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer[1][2].

Product Specifications

CAS Number

198481-33-3

Product Name Alternative

TSE-424 (acetate) (Standard)

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Reference Standards

Type

Reference Standards

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bazedoxifene-acetate-standard.html

Purity

99.65

Smiles

CC1=C(C2=CC=C(O)C=C2)N(CC3=CC=C(OCCN4CCCCCC4)C=C3)C5=CC=C(O)C=C51.CC(O)=O

Molecular Formula

C32H38N2O5

Molecular Weight

530.65

References & Citations

[1]Barry S Komm, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology. 2005 Sep;146 (9) :3999-4008.|[2]Xiaojuan Wu, et al. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy. Mol Cancer Ther. 2016 Nov; 15 (11) : 2609–2619.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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