N-Palmitoyl-D-sphingosine (Highly Pure)

<strong>N-Palmitoyl-D-sphingosine (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2018153_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 537.9_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20℃_x000D_ <strong>Keywords:</strong> Cer(d18:1/16:0), (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-1,3-diol, N-Hexadecanoyl-D-sphingosine, N-Palmitoyl-D-erythro-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexadecanamide, C16 Ceramide (d18:1/16:0), C16-Ceramide_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yamane M. Simultaneous quantitative determination method for ceramide species from crude cellular extracts by high-performance liquid chromatography-thermospray mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 5;783(1):181-90._x000D_ 2: Schmelz EM, Bushnev AS, Dillehay DL, Sullards MC, Liotta DC, Merrill AH Jr. Ceramide-beta-D-glucuronide: synthesis, digestion, and suppression of early markers of colon carcinogenesis Cancer Res. 1999 Nov 15;59(22):5768-72._x000D_ 3: Meeusen JW, Donato LJ, Bryant SC, Baudhuin LM, Berger PB, Jaffe AS. Plasma Ceramides Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1933-1939._x000D_ 4: Bibel DJ, Aly R, Shinefield HR. Antimicrobial activity of sphingosines J Invest Dermatol. 1992 Mar;98(3):269-73._x000D_ 5: Brief E, Kwak S, Cheng JT, Kitson N, Thewalt J, Lafleur M. Phase behavior of an equimolar mixture of N-palmitoyl-D-erythro-sphingosine, cholesterol, and palmitic acid, a mixture with optimized hydrophobic matching Langmuir. 2009 Jul 7;25(13):7523-32._x000D_ 6: Weis AL. New approaches to synthesis of stereospecific sphingomyelin Chem Phys Lipids. 1999 Nov;102(1-2):3-12._x000D_ 7: Dong Z, Butcher JA Jr. An efficient route to N-palmitoyl-D-erythro-sphingomyelin and its 13C-labeled derivatives Chem Phys Lipids. 1993 Nov;66(1-2):41-6._x000D_ 8: Neitchev V, Kostova E, Dimitrov AS. Importance of interfacial water in permeabilization of ceramide bilayers Histol Histopathol. 1998 Jul;13(3):911-20._x000D_ 9: Perera MN, Ganesan V, Siskind LJ, Szulc ZM, Bielawska A, Bittman R, Colombini M. Ceramide channel: Structural basis for selective membrane targeting Chem Phys Lipids. 2016 Jan;194:110-116._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29632826">10: Yamane M. Palmitoyl-ceramide accumulation with necrotic cell death in A549 cells, followed by a steep increase in sphinganine content Biochim Open. 2015 Jun 21;1:11-27. </a>_x000D_ _x000D_ <strong>Products Related to N-Palmitoyl-D-sphingosine (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals /"> Chemicals </a>