(RFR) 4XB

(RFR) 4XB is a cationic membrane-penetrating peptide. (RFR) 4XB carries its cargo (the antisense oligomer) across the outer membrane of gram-negative bacteria[1].

Product Specifications

CAS Number

[1139931-15-9]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rfr-4xb.html

Smiles

[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCCCCCC(NCCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@H](CCCNC(=N)N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O

Molecular Formula

C93H150N38O15

Molecular Weight

2040.43

References & Citations

[1]Mellbye BL, et al. Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. Antimicrob Agents Chemother. 2009 Feb;53 (2) :525-30.