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Tampramine

Tampramine (47), a phenothiazine, could reverse multidrug resistance, with ED50 values of 60 μM (P388 cells) and 60 μM (P388/ADR cells), respectively[1].

Product Specifications

CAS Number

83166-17-0

UNSPSC

12352005

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tampramine.html

Solubility

10 mM in DMSO

Smiles

CN(C)CCCN1C2=C(C=CC=C2)C(C3=CC=CC=C3)=NC4=CC=CN=C14

Molecular Formula

C23H24N4

Molecular Weight

356.46

References & Citations

[1]A Ramu, et al. Reversal of multidrug resistance by phenothiazines and structurally related compounds. Cancer Chemother Pharmacol. 1992;30 (3) :165-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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