Tampramine
Tampramine (47), a phenothiazine, could reverse multidrug resistance, with ED50 values of 60 μM (P388 cells) and 60 μM (P388/ADR cells), respectively[1].
Product Specifications
CAS Number
83166-17-0
UNSPSC
12352005
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tampramine.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCCN1C2=C(C=CC=C2)C(C3=CC=CC=C3)=NC4=CC=CN=C14
Molecular Formula
C23H24N4
Molecular Weight
356.46
References & Citations
[1]A Ramu, et al. Reversal of multidrug resistance by phenothiazines and structurally related compounds. Cancer Chemother Pharmacol. 1992;30 (3) :165-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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