Sodium citrate (dihydrate)

Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer[1][2][3].

Product Specifications

CAS Number

[6132-04-3]

Product Name Alternative

Trisodium citrate (dihydrate) ; Citric acid (trisodium salt dihydrate)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Sodium_citrate_dihydrate.html

Concentration

10mM

Purity

98.0

Solubility

10 mM in DMSO|H2O : 125 mg/mL (ultrasonic)

Smiles

O=C(CC(C(O[Na])=O)(O)CC(O[Na])=O)O[Na].O.O

Molecular Formula

C6H9Na3O9

Molecular Weight

294.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Lu P, et al. Rosmarinic Acid and Sodium Citrate Have a Synergistic Bacteriostatic Effect against Vibrio Species by Inhibiting Iron Uptake. Int J Mol Sci. 2021 Dec 1;22 (23) :13010.|[2]Guo X, et al. 3-Bromopyruvate and sodium citrate induce apoptosis in human gastric cancer cell line MGC-803 by inhibiting glycolysis and promoting mitochondria-regulated apoptosis pathway. Biochem Biophys Res Commun. 2016 Jun 17;475 (1) :37-43.|[3]Ou Y, et al. Sodium Citrate Inhibits Endoplasmic Reticulum Stress in Rats with Adenine-Induced Chronic Renal Failure. Am J Nephrol. 2015;42 (1) :14-21.