Thailanstatin A cyclohexane diamine (formic)
Thailanstatin A cyclohexane diamine formic is an analog of Spliceostatin (HY-16466) . Thailanstatin A cyclohexane diamine formic inhibits proliferations of cells N87 (IC50 is 0.33 μM), BT474 (IC50 is 0.34 μM), MDA-MB-361-DYT2 (IC50 is 0.88 μM) and MDA-MB-468 (IC50 is 0.27 μM) . Thailanstatin A cyclohexane diamine formic is used as a drug-linker conjugate for ADC molecule[1].
Product Specifications
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thailanstatin-a-cyclohexane-diamine-formic.html
Purity
93.74
Smiles
O[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C\[C@H](C)OC(C)=O)=O)C)CC(N[C@H]4CC[C@@H](CC4)N)=O)CO2.O=CO
Molecular Formula
C35H55N3O10
Molecular Weight
677.83
References & Citations
[1]DIRICO KJ, et al., Spliceostatin analogs. WO2014068443.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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