Native Canine Uromodulin

<strong>Native Canine Uromodulin</strong>_x000D_ <strong>Catalog number:</strong> B2016545_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 2 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 5-kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> Tamm-Horsfall urinary glycoprotein, THP, FJHN, HNFJ, THGP, MCKD2, ADMCKD2, UMOD, Uromodulin._x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Schweigert FJ, Raila J, Haebel S. Vitamin A excreted in the urine of canines is associated with a Tamm-Horsfall like protein Vet Res. 2002 May-Jun;33(3):299-311._x000D_ 2: Seo D, Yang Y, Hwang SH, Jung JH, Cho S, Choi G, Kim Y. Serum uromodulin in dogs with chronic kidney disease J Vet Intern Med. 2022 Nov;36(6):2071-2078._x000D_ 3: Nanamatsu A, Mori T, Ando F, Furusho T, Mandai S, Susa K, Sohara E, Rai T, Uchida S. Vasopressin Induces Urinary Uromodulin Secretion By Activating PKA (Protein Kinase A) Hypertension. 2021 Jun;77(6):1953-1963._x000D_ 4: Rindler MJ, Naik SS, Li N, Hoops TC, Peraldi MN. Uromodulin (Tamm-Horsfall glycoprotein/uromucoid) is a phosphatidylinositol-linked membrane protein J Biol Chem. 1990 Dec 5;265(34):20784-9._x000D_ 5: Gil da Costa RM, Oliveira JP, Saraiva AL, Seixas F, Faria F, G√§rtner F, Pires MA, Lopes C. Immunohistochemical characterization of 13 canine renal cell carcinomas Vet Pathol. 2011 Mar;48(2):427-32._x000D_ 6: Schaeffer C, Cattaneo A, Trudu M, Santambrogio S, Bernascone I, Giachino D, Caridi G, Campo A, Murtas C, Benoni S, Izzi C, De Marchi M, Amoroso A, Ghiggeri GM, Scolari F, Bachi A, Rampoldi L. Urinary secretion and extracellular aggregation of mutant uromodulin isoforms Kidney Int. 2012 Apr;81(8):769-78._x000D_ 7: Bernascone I, Vavassori S, Di Pentima A, Santambrogio S, Lamorte G, Amoroso A, Scolari F, Ghiggeri GM, Casari G, Polishchuk R, Rampoldi L. Defective intracellular trafficking of uromodulin mutant isoforms Traffic. 2006 Nov;7(11):1567-79._x000D_ 8: Kule≈° J, Biliƒá P, Beer Ljubiƒá B, Gotiƒá J, Crnogaj M, Brkljaƒçiƒá M, Mrljak V. Glomerular and tubular kidney damage markers in canine babesiosis caused by Babesia canis Ticks Tick Borne Dis. 2018 Sep;9(6):1508-1517._x000D_ 9: Bokhove M, Nishimura K, Brunati M, Han L, de Sanctis D, Rampoldi L, Jovine L. A structured interdomain linker directs self-polymerization of human uromodulin Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1552-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/12751332">10: Cox ML, Quignon P, Galibert F, Lees GE, Murphy KE. Sequencing and radiation hybrid mapping of canine uromodulin DNA Seq. 2003 Feb;14(1):61-9. </a>_x000D_ _x000D_ <strong>Products Related to Native Canine Uromodulin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>