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ZYZ-17

ZYZ-17 is an activator of human caseinolytic peptidase P (hClpP), with an EC50 value of 0.24 μM. ZYZ-17 can be used in anticancer research[1].

Product Specifications

CAS Number

[3065246-14-9]

UNSPSC

12352005

Target

ClpP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zyz-17.html

Smiles

O=C1N(CC2=CC=C(C(F)(F)F)C=C2)C3=NCCCN3C4=C1CN(CC4)CC5=CC(F)=CC=C5

Molecular Formula

C25H24F4N4O

Molecular Weight

472.48

References & Citations

[1]Zhang Y, et al. Development of novel imipridone derivatives with potent anti-cancer activities as human caseinolytic peptidase P (hClpP) activators. Bioorg Chem. 2024 Aug 30;153:107765.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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