Paynantheine-d3

Paynantheine-d3 is a deuterium labeled Paynantheine. Paynantheine is an alkaloid that can be isolated from Mitragyna speciosa. Paynantheine can decrease alcohol intake in mice[1][2].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

COC1=CC=CC2=C1C3=C(N2)[C@]4([H])C[C@@H]([C@H](CN4CC3)C=C)/C(C(OC([2H])([2H])[2H])=O)=C\OC

Molecular Formula

C23H25D3N2O4

Molecular Weight

399.50

References & Citations

[1]Philipp AA, et al. Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography-linear ion trap-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879 (15-16) :1049-55.|[2]Gutridge AM, et al. G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder. Br J Pharmacol. 2020 Apr;177 (7) :1497-1513.