Dihydrocephalomannine
Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel[1].
Product Specifications
CAS Number
[159001-25-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Microtubule/Tubulin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dihydrocephalomannine.html
Purity
98.04
Solubility
10 mM in DMSO
Smiles
CCC(C)C(N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@H](C(C)=C2[C@H](C([C@@]3([C@H](C[C@@H]4[C@](CO4)(OC(C)=O)[C@@]53[H])O)C)=O)OC(C)=O)C[C@](C2(C)C)([C@H]5OC(C6=CC=CC=C6)=O)O)=O)O)=O
Molecular Formula
C45H55NO14
Molecular Weight
833.92
Precautions
H302, H315, H319, H335
References & Citations
[1]Paclitaxel Analogue
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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