S100B Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
Abbreviation
S100B
UniProt
P50114
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant Mouse S100B protein expressed by E.coli
Target
NEF; Protein S100 B; S 100 calcium binding protein beta chain; S100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium-binding protein B; S100B; S100beta
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:75-1:150
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Documents
Curated Selection
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