BTK ligand 11

BTK ligand 11 is a PROTAC target protein ligand that can be used to synthesize BCPyr (HY-142621) [1].

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/btk-ligand-11.html

Smiles

FC1=CC=C(OC2=CC=C(C3=NN([C@H]4CN(C(O)=O)CCC4)C(N)=C3C(N)=O)C=C2)C(F)=C1

Molecular Formula

C22H21F2N5O4

Molecular Weight

457.43

References & Citations

[1]James Schiemer, et al. Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes. Nat Chem Biol. 2021 Feb;17 (2) :152-160.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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