BTK ligand 11
BTK ligand 11 is a PROTAC target protein ligand that can be used to synthesize BCPyr (HY-142621) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-ligand-11.html
Smiles
FC1=CC=C(OC2=CC=C(C3=NN([C@H]4CN(C(O)=O)CCC4)C(N)=C3C(N)=O)C=C2)C(F)=C1
Molecular Formula
C22H21F2N5O4
Molecular Weight
457.43
References & Citations
[1]James Schiemer, et al. Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes. Nat Chem Biol. 2021 Feb;17 (2) :152-160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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