Buflomedil (hydrochloride)
Buflomedil hydrochloride, a vasodilator agent, is an orally active α1A-adrenoceptor antagonist with Kis of 4.06 µM and 6.84 µM for α1A-AR and α1B-AR, respectively. Buflomedil hydrochloride can be used for the study of peripheral circulatory disorders[1][2].
Product Specifications
CAS Number
[35543-24-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Buflomedil-hydrochloride.html
Purity
99.81
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : ≥ 55 mg/mL
Smiles
O=C(C1=C(OC)C=C(OC)C=C1OC)CCCN2CCCC2.Cl
Molecular Formula
C17H26ClNO4
Molecular Weight
343.85
Precautions
H302, H315, H319, H335
References & Citations
[1]http://www.medscape.com/viewarticle/753768|[2]Tang LM, et al. Inhibitory effect of buflomedil on prostate alpha1A adrenoceptor in the Wistar rat. Neurosci Lett. 2004 Sep 2;367 (2) :224-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor
Available Sizes
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