Ganodermanontriol
Product Specifications
UNSPSC Description
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity[1][2].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ganodermanontriol.html
Purity
97.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1(C)C(CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC[C@H](O)[C@](C)(O)CO)CC[C@](C)4C3=CC[C@@]12[H])=O
Molecular Weight
472.70
References & Citations
[1]Kennedy EM, et al. Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. J Nat Prod. 2011 Nov 28;74(11):2332-7.|[2]Ha do T, et al. In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. Ethnopharmacol. 2013 Dec 12;150(3):875-85.|[3]Jedinak A, Thyagarajan-Sahu A, Jiang J, Sliva D. Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling. Int J Oncol. 2011;38(3):761-767.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N1506/Ganodermanontriol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N1506/Ganodermanontriol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
106518-63-2
Available Sizes
Curated Selection
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