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TBDMS-PEG4-OH

TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[134179-40-1]

UNSPSC

12352211

Hazard Statement

H301, H315

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tbdms-peg4-oh.html

Purity

97.0

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CC(C)([Si](C)(OCCOCCOCCOCCO)C)C

Molecular Formula

C14H32O5Si

Molecular Weight

308.49

Precautions

H301, H315

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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