CCR6 antagonist 1
CCR6 antagonist 1 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs) [1].
Product Specifications
CAS Number
588674-64-0
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ccr6-antagonist-1.html
Purity
99.30
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=C(C)C2=CC=CC=C2O1)NC3=CC=C(C(F)(F)F)C=C3
Molecular Formula
C17H12F3NO2
Molecular Weight
319.28
References & Citations
[1]Maria Grazia Martina, et al. Discovery of small-molecules targeting the CCL20/CCR6 axis as first-in-class inhibitors for inflammatory bowel diseases. Eur J Med Chem. 2022 Aug 29;243:114703.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR6
Available Sizes
Frequently Asked Questions
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