Conodurine
Conodurine is a monoterpenoid indole alkaloid. Conodurine can inhibit lysosomal acidification. Conodurineis isolated from the natural Tabernaemontana corymbosa[1].
Product Specifications
CAS Number
2665-57-8
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/conodurine.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]1(C(OC)=O)[C@@](CC2=C([C@@H](C3=C(OC)C=CC4=C3NC5=C4CCN(C6)[C@]7([H])[C@@]5(C(OC)=O)C[C@@]6([H])C[C@]7([H])CC)C[C@]/81[H])NC9=C2C=CC=C9)([H])N(C)CC8=C\C
Molecular Formula
C43H52N4O5
Molecular Weight
704.90
References & Citations
[1]Zhang Y, Ding X, Yuan YX, Guo LL, Hao XJ. Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification. J Nat Prod. 2020 May 22;83 (5) :1432-1439.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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