Anti-NASH agent 1
Anti-NASH agent 1 (compound 3d), a derivative of Elafibranor , is a potent agonist of PPAR-α/δ, targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia, liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1].
Product Specifications
CAS Number
2409685-41-0
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-nash-agent-1.html
Purity
98.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(OC1=C(C)C=C(/C=C/C(C2=CC=C(NC)C=C2)=O)C=C1C)C(OC(C)(C)C)=O
Molecular Formula
C26H33NO4
Molecular Weight
423.54
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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