Prolylrapamycin
Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin. Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL[1].
Product Specifications
CAS Number
156223-31-3
Product Name Alternative
21-Norrapamycin
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/prolylrapamycin.html
Smiles
O=C([C@@](CCC1)([H])N1C(C([C@@]2(O)[C@H](C)CC[C@@](O2)([H])C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@H]3C)=O)=O)=O)O[C@H]([C@H](C)C[C@H]4C[C@@H](OC)[C@H](O)CC4)CC3=O
Molecular Formula
C50H77NO13
Molecular Weight
900.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wong GK, et al., Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. J Antibiot (Tokyo) . 1998 May;51 (5) :487-91.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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