Ac-IEPD-AMC (TFA)

Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC) . AMC fluoresces under UV light irradiation and can emit fluorescent signals[1].

Product Specifications

UNSPSC

12352209

Target

Fluorescent Dye

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-iepd-amc-tfa.html

Purity

98.01

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H]2N(CCC2)C([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)=O)=O)=O)C=C1O3)=CC3=O.OC(C(F)(F)F)=O.[x]

Molecular Formula

C32H41N5O11.xC2HF3O2

Molecular Weight

671.69 (free acid)

References & Citations

[1]Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60 (11) :5699-5703. [Content Brief]