Trans-Resveratrol-3-O-β-D-Glucuronide

Trans-Resveratrol-3-O-β-D-Glucuronide is an active metabolite of trans-resveratrol. trans-Resveratrol-3-O-β-D-Glucuronide reduces the proliferation of several intestinal cancer cell line. trans-Resveratrol-3-O-β-D-Glucuronide increases pyruvate production in livers[1][2][3].

Product Specifications

CAS Number

[387372-17-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/trans-resveratrol-3-o-β-d-glucuronide.html

Purity

96.91

Solubility

10 mM in DMSO

Smiles

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC(/C=C/C3=CC=C(C=C3)O)=CC(O)=C2)=O

Molecular Formula

C20H20O9

Molecular Weight

404.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Rousova J, et al. Determination of trans-resveratrol and its metabolites in rat serum using liquid chromatography with high-resolution time of flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1039:35-43. |[2]Polycarpou E, et al. Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest. Mol Nutr Food Res. 2013;57 (10) :1708-1717. |[3]Simões MS, et al. Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats. Life Sci. 2022;310:120991.